Ghana Immigration Service and Police officers conducted a raid in Pakyi, Amansie West.
The operation resulted in the arrest of 28 foreign nationals.
A landlord who allegedly housed the foreigners was also apprehended.
Authorities stated the arrests were made for suspected violations of Ghana's immigration laws.
The specific nationalities of the arrested individuals were not immediately disclosed.
Further investigations are being carried out by the security agencies.
The Amansie West District Assembly supported the joint security operation.
Officials are working to confirm the legal status of the apprehended individuals in Ghana.