Immigration and police officers conducted a raid in Pakyi, Amansie West.
The operation led to the arrest of 28 foreign nationals.
A landlord was also arrested during the joint operation.
Authorities stated the individuals are suspected of violating Ghana's immigration laws.
The Amansie West District Assembly participated in the exercise.
Further investigations are expected.
The exact nationalities of the arrested individuals have not been disclosed.
The landlord is accused of harbouring individuals without proper documentation.