The Narcotic Control Commission and the Ghana Police Service worked together to make the arrest.
The operation took place at a checkpoint in the Volta Region.
Two individuals were apprehended during the raid.
Officers discovered 107 kilograms of cocaine in their possession.
The drugs have been seized as evidence.
Investigations into the matter are ongoing.
Authorities are working to determine the origin and intended destination of the cocaine.
This action is part of ongoing efforts to combat illegal drug trafficking in Ghana.